Corpus ID: 37359709

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

@article{Reitzer1979EvidenceTG,
  title={Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.},
  author={L. J. Reitzer and B. Wice and D. Kennell},
  journal={The Journal of biological chemistry},
  year={1979},
  volume={254 8},
  pages={
          2669-76
        }
}
  • L. J. Reitzer, B. Wice, D. Kennell
  • Published 1979
  • Biology, Medicine
  • The Journal of biological chemistry
  • Cultured HeLa cells grew at a similar rate when the sugar source was either glucose, galactose, or fructose. The relative rates of carbon flow through glycolysis and the pentose phosphate cycle, as well as total utilization, were a function both of the sugar and its concentration. When 21 mu, about 80% of the glucose carbon was metabolized through glycolysis to lactic acid, but only 4 to 5% of sugar carbon entered the citric acid cycle. At the other extreme, on 2 mu fructose about 100 times… CONTINUE READING
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