Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with on-line continuous monitoring of glutamate

@article{Ueda1994EvidenceTG,
  title={Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with on-line continuous monitoring of glutamate},
  author={Mutsuaki Ueda and Yasushi Kuraishi and Kanji Sugimoto and Masamichi Satoh},
  journal={Neuroscience Research},
  year={1994},
  volume={20},
  pages={231-237}
}
The aim of this study is to elucidate whether the excitatory amino acid glutamate is released from capsaicin-sensitive primary afferent fibers, and to compare the releasing effect of capsaicin on glutamate with that on substance P. The release of glutamate was measured using a fluorometric on-line continuous monitoring system, in which the immobilized glutamate dehydrogenase column was connected to an in vitro superfusion system. In the presence of 0.3 microM tetrodotoxin, 2-min application of… CONTINUE READING

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