Evidence that galanin is a parasympathetic, rather than a sympathetic, neurotransmitter in the baboon pancreas.

@article{Verchere1996EvidenceTG,
  title={Evidence that galanin is a parasympathetic, rather than a sympathetic, neurotransmitter in the baboon pancreas.},
  author={C Bruce Verchere and Stephan Kowalyk and D J Koerker and Denis G. Baskin and Gerald J. Taborsky},
  journal={Regulatory peptides},
  year={1996},
  volume={67 2},
  pages={93-101}
}
To determine whether galanin is a pancreatic sympathetic neurotransmitter regulating insulin secretion in the baboon, as it is in the dog, we evaluated galanin for inhibitory effects on insulin secretion in conscious baboons, determined if baboon pancreatic islets are innervated by galaninergic fibers using immunohistochemistry, and measured galanin content in the major sympathetic ganglion supplying the pancreas. Surprisingly, infusion of galanin (1 microgram/kg per min) had no effect on… CONTINUE READING

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