Evidence that exposure to methyl mercury during gestation induces behavioral and neurochemical changes in offspring of rats.

@article{Cagiano1990EvidenceTE,
  title={Evidence that exposure to methyl mercury during gestation induces behavioral and neurochemical changes in offspring of rats.},
  author={Raffaele Cagiano and Maria Antonietta De Salvia and Giuseppe Renna and E Tortella and Daniela Braghiroli and Carmela Parenti and Paola Zanoli and Mario Baraldi and Zoltan Annau and Vincenzo Cuomo},
  journal={Neurotoxicology and teratology},
  year={1990},
  volume={12 1},
  pages={23-8}
}
On day 15 of gestation, pregnant Sprague-Dawley rats were orally treated by gavage with 8 mg/kg of methyl mercury (MMC). At day 1 of postnatal life the levels of MMC in whole brain of exposed pups were found to be about 100 times higher than those of saline-exposed rats, while they were near to the control values at 21 days and practically normal at 60 days of age. Behavioral experiments showed that exposure to MMC in late gestation did not affect at any tested time (14, 21 and 60 days… CONTINUE READING