Evidence that both protium and deuterium undergo significant tunneling in the reaction catalyzed by bovine serum amine oxidase.

@article{Grant1989EvidenceTB,
  title={Evidence that both protium and deuterium undergo significant tunneling in the reaction catalyzed by bovine serum amine oxidase.},
  author={Kathleen L. Grant and Judith P Klinman},
  journal={Biochemistry},
  year={1989},
  volume={28 16},
  pages={6597-605}
}
The magnitudes of primary and secondary H/T and D/T kinetic isotope effects have been measured in the bovine serum amine oxidase catalyzed oxidation of benzylamine from 0 to 45 degrees C. Secondary H/T and D/T kinetic effects are small and in the range anticipated from equilibrium isotope effects; Arrhenius preexponential factors (AH/AT and AD/AT… CONTINUE READING