Evidence that axons are mitogenic for oligodendrocytes isolated from adult animals


Recovery from demyelinating events in the adult central nervous system (CNS) may depend in some situations on the generation, by cell division, of new oligodendrocytes (ODCs)1. Adult ODCs, identified by morphological criteria, have been shown to divide in vivo in response to induced demyelination or to physical trauma2,3, although the factors that elicit… (More)
DOI: 10.1038/320756a0


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