Evidence that alpha(1B)-adrenoceptors are involved in noradrenaline-induced contractions of rat tail artery.

@article{Jhnichen2004EvidenceTA,
  title={Evidence that alpha(1B)-adrenoceptors are involved in noradrenaline-induced contractions of rat tail artery.},
  author={Sven J{\"a}hnichen and Manfrid Eltze and Heinz H. Pertz},
  journal={European journal of pharmacology},
  year={2004},
  volume={488 1-3},
  pages={157-67}
}
The present study characterizes the alpha(1)-adrenoceptor subtypes mediating contractions to noradrenaline in isolated ring preparations of rat tail artery. Concentration-response (E/[A]) curves to noradrenaline were apparently monophasic (pEC(50) 6.47) but became biphasic in the presence of the selective alpha(1A)-adrenoceptor antagonist (+/-)-1,3,5-trimethyl-6-[[3-[4-((2,3-dihydro-2-hydroxymethyl)-1,4-benzodioxin-5-yl)-1-piperazinyl]propyl]amino]-2,4(1H,3H)-pyrimidinedione (B8805-033… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

α1-Adrenoceptors in proximal segments of tail arteries from control and reserpinised rats

Naunyn-Schmiedeberg's Archives of Pharmacology • 2007
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…