Evidence that a septin diffusion barrier is dispensable for cytokinesis in budding yeast.

@article{Wloka2011EvidenceTA,
  title={Evidence that a septin diffusion barrier is dispensable for cytokinesis in budding yeast.},
  author={Carsten Wloka and Ryuichi Nishihama and Masayuki Onishi and Younghoon Oh and Julia Hanna and John R. Pringle and Michael Krauss and Erfei Bi},
  journal={Biological chemistry},
  year={2011},
  volume={392 8-9},
  pages={813-29}
}
Septins are essential for cytokinesis in Saccharomyces cerevisiae, but their precise roles remain elusive. Currently, it is thought that before cytokinesis, the hourglass-shaped septin structure at the mother-bud neck acts as a scaffold for assembly of the actomyosin ring (AMR) and other cytokinesis factors. At the onset of cytokinesis, the septin hourglass splits to form a double ring that sandwiches the AMR and may function as diffusion barriers to restrict diffusible cytokinesis factors to… CONTINUE READING