Evidence that HLA-Cw6 determines early onset of psoriasis, obtained using sequence-specific primers (PCR-SSP).

@article{Enerbck1997EvidenceTH,
  title={Evidence that HLA-Cw6 determines early onset of psoriasis, obtained using sequence-specific primers (PCR-SSP).},
  author={C Enerb{\"a}ck and Tommy Martinsson and Annica Inerot and J. G. Wahlstr{\"o}m and Fredrik Enlund and Maria Yhr and Gunnar Swanbeck},
  journal={Acta dermato-venereologica},
  year={1997},
  volume={77 4},
  pages={273-6}
}
Psoriasis vulgaris has previously been shown to associate with certain HLA alleles. HLA-Cw6 is considered to be the primary association, based on calculations of relative risk after serological typing. This association is reportedly more pronounced in early- than in late-onset psoriasis. We performed a PCR-based typing with sequence-specific primers, which has been shown to give a more complete result than serology. Two hundred and one unrelated patients with psoriasis, with a mean age of 40… CONTINUE READING