Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia. Young Investigator Award.

@article{Chaiworapongsa2004EvidenceSA,
  title={Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia. Young Investigator Award.},
  author={Tinnakorn Chaiworapongsa and Roberto Romero and Jimmy Espinoza and Emmanuel Bujold and Yeon Mee Kim and Luis Fl{\'a}vio Galv{\~a}o Gonçalves and Ricardo Pay{\'a}n Gom{\'e}z and Samuel S. Edwin},
  journal={American journal of obstetrics and gynecology},
  year={2004},
  volume={190 6},
  pages={1541-7; discussion 1547-50}
}
OBJECTIVE Soluble vascular endothelial growth factor receptor 1 (sVEGFR-1), which antagonizes VEGF functions, has been implicated in the pathophysiology of preeclampsia. The purpose of this study was to determine whether preeclampsia is associated with a change in the plasma concentration of sVEGFR-1, and, if so, whether such a change is correlated with the severity of the disease. METHODS A cross-sectional study was conducted to determine the concentrations of sVEGFR-1 in plasma obtained… CONTINUE READING