Evidence relating human verbal memory to hippocampal N-methyl-D-aspartate receptors.

  title={Evidence relating human verbal memory to hippocampal N-methyl-D-aspartate receptors.},
  author={Thomas Grunwald and Heinz Beck and Klaus Lehnertz and Ingmar Bl{\"u}mcke and Nico Pezer and Martin Kurthen and Guill{\'e}n Fern{\'a}ndez and Dirk van Roost and Hans Jochen Heinze and Marta Kutas and Christian Erich Elger},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={96 21},
Studies in rodents and nonhuman primates have linked the activity of N-methyl-D-aspartate (NMDA) receptors within the hippocampus to animals' performance on memory-related tasks. However, whether these receptors are similarly essential for human memory is still an open question. Here we present evidence suggesting that hippocampal NMDA receptors, most likely within the CA1 region, do participate in human verbal memory processes. Words elicit a negative event-related potential (ERP) peaking… CONTINUE READING


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