Evidence of white matter changes on diffusion tensor imaging in frontotemporal dementia.

  title={Evidence of white matter changes on diffusion tensor imaging in frontotemporal dementia.},
  author={Barbara Borroni and Simona Maria Brambati and Chiara Agosti and Stefano Gipponi and Giuseppe Bellelli and Roberto Gasparotti and Valentina Garibotto and Monica Di Luca and Paola Scifo and Daniela Perani and Alessandro Padovani},
  journal={Archives of neurology},
  volume={64 2},
BACKGROUND Two major clinical variants of frontotemporal dementia (FTD) have been described: frontal variant (fvFTD) and temporal variant (tvFTD). OBJECTIVE To analyze white matter (WM) and gray matter (GM) tissue organization in patients with fvFTD and tvFTD by means of diffusion tensor imaging and voxel-based morphometry, and the correlations with neuropsychological and behavioral variables. DESIGN AND SETTING Frontotemporal dementia clinic-based cohort and structural magnetic resonance… CONTINUE READING


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