Evidence of undiscovered cell regulatory mechanisms: phosphoproteins and protein kinases in mitochondria

@article{Thomson2002EvidenceOU,
  title={Evidence of undiscovered cell regulatory mechanisms: phosphoproteins and protein kinases in mitochondria},
  author={Murray Thomson},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2002},
  volume={59},
  pages={213-219}
}
The finding that mitochondria contain substrates for protein kinases lead to the discovery that protein kinases are located in the mitochondria of certain tissues and species. These include pyruvate dyhydrogenase kinase, branched-chain α-ketoacid dehydrogenase kinase, protein kinase A, protein kinase Cδ, stress-activated kinase and A-Raf as well as unidentified kinases. Recent evidence suggests that mitochondrial protein kinases may be involved in physiological processes such as apoptosis and… CONTINUE READING

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