Evidence of systemic cytokine release in patients undergoing cardiopulmonary bypass.

@article{Halter2005EvidenceOS,
  title={Evidence of systemic cytokine release in patients undergoing cardiopulmonary bypass.},
  author={Jeffrey M Halter and Jay Steinberg and Gregory Fink and Charles Lutz and Anthony Picone and Rubie Sue Maybury and Nathan Holt Fedors and Joseph D Dirocco and Hsi-Ming Lee and Gary F. Nieman},
  journal={The journal of extra-corporeal technology},
  year={2005},
  volume={37 3},
  pages={272-7}
}
Cardiopulmonary bypass (CPB) causes a systemic inflammatory response syndrome (SIRS), which can progress to an acute lung inflammation known as postperfusion syndrome. We developed a two-phase hypothesis: first, that SIRS, as indicated by elevated cytokines post-CPB, would be correlated with postoperative pulmonary dysfunction (Phase I), and second, that the cytokine interleukin-6 (IL-6) is predominantly released from the heart in CPB patients (Phase II). Blood samples were collected from… CONTINUE READING
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MesanaT. The inflammatory response to cardiopulmonary bypass: A therapeutic overview. Perfusion. 2004;19(Suppl 1):S5–12

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MesanaT . The inflammatory response to cardiopulmonary bypass : A therapeutic overview

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