Evidence of pleiotropic loci for fasting insulin, total fat mass, and abdominal visceral fat in a sedentary population: the HERITAGE family study.

@article{Hong2000EvidenceOP,
  title={Evidence of pleiotropic loci for fasting insulin, total fat mass, and abdominal visceral fat in a sedentary population: the HERITAGE family study.},
  author={Yuling Hong and J P Despr{\'e}s and Treva Rice and Andr{\'e} Nadeau and Michael A. Province and Jacques Gagnon and Arthur S. Leon and James S. Skinner and Jack H. Wilmore and Claude Bouchard and D. Chandrasekhra Rao},
  journal={Obesity research},
  year={2000},
  volume={8 2},
  pages={151-9}
}
OBJECTIVE To examine whether there is a major gene effect on fasting insulin and pleiotropic loci for fasting insulin, total fat mass (FM), and abdominal visceral fat (AVF). RESEARCH METHODS AND PROCEDURES A major gene hypothesis for fasting plasma insulin levels was assessed using segregation analyses of data on 495 members in 98 normolipidemic sedentary… CONTINUE READING