Evidence of oxidative stress in peroxisomal disorders.

  title={Evidence of oxidative stress in peroxisomal disorders.},
  author={Hala T El-Bassyouni and Soheir A Abdel Maksoud and Fadia A Salem and Reem Badr El-Deen and Hisham Abdel Aziz and Manal Michel Thomas},
  journal={Singapore medical journal},
  volume={53 9},
INTRODUCTION Peroxisomal disorders are subdivided into peroxisome biogenesis disorders (PBDs) and single peroxisomal enzyme deficiency. Many peroxisomal diseases exhibit excessive oxidative stress, leading to neurological alterations and dysfunction. Peroxisomes use oxygen in oxidative reactions that generate hydrogen peroxide. This study aimed to investigate various oxidative stress parameters in patients suffering from peroxisomal disorders. METHODS A total of 20 patients with peroxisomal… CONTINUE READING
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