Evidence of oxidative damage and reproductive dysfunction accompanying 4-vinylcyclohexene diepoxide exposure in female Wistar rats.

Abstract

4-Vinylcyclohexene diepoxide (VCD) is an occupational chemical widely reported to deplete ovarian follicles in rodents. Here, we investigated VCD-induced reproductive dysfunction in female Wistar rats. The rats were orally administered with VCD (100, 250 and 500mg/kg) for twenty-eight days. Thereafter, we evaluated selected biomarkers of oxidative damage… (More)
DOI: 10.1016/j.reprotox.2016.09.009

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@article{Abolaji2016EvidenceOO, title={Evidence of oxidative damage and reproductive dysfunction accompanying 4-vinylcyclohexene diepoxide exposure in female Wistar rats.}, author={Amos O Abolaji and Isaac Adegboyega Adedara and Ayodeji O Abajingin and Ore J Fatunmibi and Emmanuel O Ladipo and Ebenezer Olatunde Farombi}, journal={Reproductive toxicology}, year={2016}, volume={66}, pages={10-19} }