Evidence of multiple pyrethroid resistance mechanisms in the malaria vector Anopheles gambiae sensu stricto from Nigeria.

@article{Awolola2009EvidenceOM,
  title={Evidence of multiple pyrethroid resistance mechanisms in the malaria vector Anopheles gambiae sensu stricto from Nigeria.},
  author={Taiwo Samson Awolola and O A Oduola and Clare Strode and Lizette Leonie Koekemoer and Basil D. Brooke and Hilary Ranson},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  year={2009},
  volume={103 11},
  pages={1139-45}
}
Pyrethroid insecticide resistance in Anopheles gambiae sensu stricto is a major concern to malaria vector control programmes. Resistance is mainly due to target-site insensitivity arising from a single point mutation, often referred to as knockdown resistance (kdr). Metabolic-based resistance mechanisms have also been implicated in pyrethroid resistance in East Africa and are currently being investigated in West Africa. Here we report the co-occurrence of both resistance mechanisms in a… CONTINUE READING

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