Evidence of genetic locus heterogeneity for familial bicuspid aortic valve.


OBJECTIVE We sought to determine if the gene responsible for bicuspid aortic valve (BAV) in an extended family corresponds to previously reported loci for inherited forms of the disorder. BACKGROUND Loci at 15q25.1-26 and 9q34 have been reported to be associated with cardiovascular abnormalities involving BAV. METHODS Linkage analysis was performed on… (More)


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