Evidence of gastro-intestinal system as an active and toxic target of sasanqua saponins extract.

Sasanqua saponins extract (SSE) was prepared from the remainder of seeds of Camellia sasanqua after oil extract using ethanol as solvent. We have now evaluated the acute and subchronic toxicity of SSE by oral route in mice. A single oral administration of SSE (125-2000 mg/kg) produced a dose-dependent increase in adverse effects and the mortality rate of… CONTINUE READING