Evidence of familial association between attention deficit disorder and major affective disorders.

@article{Biederman1991EvidenceOF,
  title={Evidence of familial association between attention deficit disorder and major affective disorders.},
  author={Joseph Biederman and Stephen V Faraone and Kate Keenan and Ming T. Tsuang},
  journal={Archives of general psychiatry},
  year={1991},
  volume={48 7},
  pages={
          633-42
        }
}
With the use of family study methods and assessments by "blinded" raters, we tested hypotheses about patterns of familial association between DSM-III attention deficit disorder (ADD) and affective disorders (AFFs) among first-degree relatives of clinically referred children and adolescents with ADD (73 probands, 264 relatives) and normal controls (26 probands, 92 relatives). Among the 73 ADD probands, 24 (33%) met criteria for AFFs (major depression, n = 15 [21%]; bipolar disorder, n = 8 [11… CONTINUE READING

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