Evidence of eosinophil, neutrophil, and mast-cell mediators in the effusion of OME patients with and without atopy.

@article{Hurst2000EvidenceOE,
  title={Evidence of eosinophil, neutrophil, and mast-cell mediators in the effusion of OME patients with and without atopy.},
  author={David S Hurst and Per Venge},
  journal={Allergy},
  year={2000},
  volume={55 5},
  pages={435-41}
}
BACKGROUND This study was designed to measure the involvement of eosinophils, neutrophils, and mast cells in the middle ear of patients with OME and to see whether that inflammatory response differed depending on whether or not the patient was atopic. METHODS Levels of ECP, MPO, and tryptase were measured in effusion from 97 patients whose atopic status was determined by in vitro testing with 12 inhalants and five foods. RESULTS Seventy-nine of 97 OME patients (81%) were atopic, among whom… CONTINUE READING

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