Evidence of enhancement of malate-aspartate shuttle activity in beta cells of streptozotocin-induced non-insulin-dependent diabetic rats.

@article{Song2000EvidenceOE,
  title={Evidence of enhancement of malate-aspartate shuttle activity in beta cells of streptozotocin-induced non-insulin-dependent diabetic rats.},
  author={Dae-Kyu Song and Young Hwan Ahn and Jae Hoon Bae and Won Kyun Park and Young Shick Hong and Won Kyung Ho and Yung E. Earm},
  journal={Metabolism: clinical and experimental},
  year={2000},
  volume={49 1},
  pages={92-6}
}
Glucose-induced insulin secretion is selectively impaired in beta cells from animals with non-insulin-dependent diabetes mellitus (NIDDM). This study was performed to clarify whether the malate-aspartate shuttle among the glucose metabolic pathways is intact in beta cells of NIDDM rats. The insulin secretory capacity of the islets and the K(ATP) channel… CONTINUE READING