Evidence of endothelial progenitor cells in the human brain and spinal cord arteriovenous malformations.

@article{Gao2010EvidenceOE,
  title={Evidence of endothelial progenitor cells in the human brain and spinal cord arteriovenous malformations.},
  author={Peng Gao and Yongmei Chen and M T Lawton and Nicholas M. Barbaro and Guo-Yuan Yang and Hua Su and Feng Ling and William L. Young},
  journal={Neurosurgery},
  year={2010},
  volume={67 4},
  pages={1029-35}
}
BACKGROUND Brain and spinal cord arteriovenous malformations (AVMs) are characterized by aberrant angiogenesis and vascular remodeling. Endothelial progenitor cells (EPCs) can be recruited by stromal cell-derived factor-1 (SDF-1), and participate in vascular remodeling in both physiological and pathological settings. OBJECTIVE To investigate whether there are increased EPC levels in the brain and spinal cord AVM nidus. METHODS Microsurgical specimens without endovascular embolization and… CONTINUE READING