Evidence of depression provoked by cardiovascular medication: a prescription sequence symmetry analysis.

@article{Hallas1996EvidenceOD,
  title={Evidence of depression provoked by cardiovascular medication: a prescription sequence symmetry analysis.},
  author={Jesper Hallas},
  journal={Epidemiology},
  year={1996},
  volume={7 5},
  pages={
          478-84
        }
}
Many cardiovascular drugs have been implicated as causes of depression. With the exception of beta-blockers, few have been studied in formal epidemiologic designs. I present a new approach to such analyses that effectively controls for confounders that are stable over time. I analyzed the exposure histories of 11,244 incident antidepressant users, using the Odense University PharmacoEpidemiologic Database. All persons starting both beta-blockers and antidepressants during a predefined period… CONTINUE READING
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