Evidence of changes in renal charge selectivity in patients with Type 1 (insulin-dependent) diabetes mellitus

Abstract

Altered filtration of macromolecules due to decreased electrical charge of the glomerular basement membrane might be the initial step in the development of albuminuria in patients with Type 1 (insulin-dependent) diabetes mellitus. We therefore investigated the selectivity index, i. e. renal clearance of non-glycated plasma albumin/clearance of glycated… (More)
DOI: 10.1007/BF00869262

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