Evidence of changes in renal charge selectivity in patients with Type 1 (insulin-dependent) diabetes mellitus


Altered filtration of macromolecules due to decreased electrical charge of the glomerular basement membrane might be the initial step in the development of albuminuria in patients with Type 1 (insulin-dependent) diabetes mellitus. We therefore investigated the selectivity index, i. e. renal clearance of non-glycated plasma albumin/clearance of glycated… (More)
DOI: 10.1007/BF00869262

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