Evidence of autoantibodies to cell membrane associated DNA (cultured lymphocytes): a new specific marker for rapid identification of systemic lupus erythematosus.

@article{Servais1998EvidenceOA,
  title={Evidence of autoantibodies to cell membrane associated DNA (cultured lymphocytes): a new specific marker for rapid identification of systemic lupus erythematosus.},
  author={Genevi{\`e}ve Servais and Marie Paule Guillaume and Nicolas E Dumarey and Jean Duchateau},
  journal={Annals of the rheumatic diseases},
  year={1998},
  volume={57 10},
  pages={606-13}
}
OBJECTIVE Autoantibodies to cell membrane associated DNA are described in systemic lupus erythematosus (SLE). The specificity of these antibodies differ from antibodies to nuclear DNA. METHODS Using indirect immunofluorescence, a specific IgG was detected giving a characteristic pattern of continuous peripheral membrane fluorescence on cultured B-lymphocytes. RESULTS This pattern was observed in 53 of 80 serum samples of SLE patients but absent in the serum samples of the control… CONTINUE READING
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Prevalence and characteristics of anti single stranded DNA antibodies in localized scleroderma . Comparison with systemic lupus erythematosus

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