Evidence of augmented central pain processing in idiopathic chronic low back pain.

@article{Giesecke2004EvidenceOA,
  title={Evidence of augmented central pain processing in idiopathic chronic low back pain.},
  author={Thorsten Giesecke and Richard H. Gracely and Masilo A B Grant and Alf Nachemson and Frank W Petzke and David A. Williams and Daniel J. Clauw},
  journal={Arthritis and rheumatism},
  year={2004},
  volume={50 2},
  pages={
          613-23
        }
}
OBJECTIVE For many individuals with chronic low back pain (CLBP), there is no identifiable cause. In other idiopathic chronic pain conditions, sensory testing and functional magnetic resonance imaging (fMRI) have identified the occurrence of generalized increased pain sensitivity, hyperalgesia, and altered brain processing, suggesting central augmentation of pain processing in such conditions. We compared the results of both of these methods as applied to patients with idiopathic CLBP (n = 11… CONTINUE READING
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