Evidence of aspirin use in both upper and lower gastrointestinal perforation.

@article{Lanas1997EvidenceOA,
  title={Evidence of aspirin use in both upper and lower gastrointestinal perforation.},
  author={A. Iriarte Lanas and Pedro Hernandez Serrano and Eduardo Bajador and Francisco Esteva and Rafael Benito and Ricardo S{\'a}inz},
  journal={Gastroenterology},
  year={1997},
  volume={112 3},
  pages={683-9}
}
BACKGROUND & AIMS Current studies lack appropriate data on aspirin and other risk factors for gastrointestinal perforation. The aim of this study was to obtain the best estimate on aspirin and nonaspirin nonsteroidal anti-inflammatory drug (NSAID) use in these patients. METHODS In 76 consecutive patients with gastrointestinal perforation and 152 matched controls, a detailed clinical history supplemented with an objective test of current aspirin use (platelet cyclooxygenase activity) was… CONTINUE READING