Evidence of apoptosis in arrhythmogenic right ventricular dysplasia.

  title={Evidence of apoptosis in arrhythmogenic right ventricular dysplasia.},
  author={Ziad Mallat and Alain Tedgui and Fabrice Fontaliran and Robert I. Frank and M. Durigon and Guy Hugues Fontaine},
  journal={The New England journal of medicine},
  volume={335 16},
BACKGROUND Arrhythmogenic right ventricular dysplasia, a disorder that may lead to severe ventricular arrhythmias and sudden death, is characterized by the progressive replacement of myocardial cells by fat and fibrous tissue. We examined whether the loss of myocardial cells in this disease could result from cell death by apoptosis (programmed cell death). METHODS Specimens obtained at autopsy from the right ventricular myocardium of eight patients with arrhythmogenic right ventricular… CONTINUE READING
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