Evidence of an association between the scavenger receptor class B member 2 gene and Parkinson's disease

@article{Michelakakis2012EvidenceOA,
  title={Evidence of an association between the scavenger receptor class B member 2 gene and Parkinson's disease},
  author={H. Michelakakis and G. Xiromerisiou and E. Dardiotis and M. Bozi and D. Vassilatis and P. Kountra and Gianna Patramani and M. Moraitou and D. Papadimitriou and E. Stamboulis and L. Stefanis and E. Zintzaras and G. Hadjigeorgiou},
  journal={Movement Disorders},
  year={2012},
  volume={27}
}
Lysosomal protein 2 (LIMP2), the product of the scavenger receptor class B member 2 (SCARB2) gene, is a ubiquitously expressed transmembrane protein that is the mannose‐6‐phosphate–independent receptor for glucocerebrosidase (β‐GCase); a deficiency in this protein causes Gaucher disease. Several studies have shown a link between mutations in the β‐GCase gene and diseases characterized clinically by Parkinsonism and by the presence of Lewy body–related pathology. We hypothesized that genetic… Expand
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TLDR
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