Evidence of airway inflammation and remodeling in ski athletes with and without bronchial hyperresponsiveness to methacholine.

@article{Karjalainen2000EvidenceOA,
  title={Evidence of airway inflammation and remodeling in ski athletes with and without bronchial hyperresponsiveness to methacholine.},
  author={Elisa Karjalainen and Annika Laitinen and Malcolm Sue-Chu and Alan Altraja and Leif Bjermer and Lauri A. Laitinen},
  journal={American journal of respiratory and critical care medicine},
  year={2000},
  volume={161 6},
  pages={2086-91}
}
Asthma-like symptoms, methacholine hyperresponsiveness, and use of asthma medication are prevalent in elite cross-country skiers. We quantitated mucosal inflammatory cell infiltration and tenascin expression in the subepithelial basement membrane in endobronchial biopsy specimens of the proximal airways from 40 elite, competitive skiers (mean: 17.5; range: 16 to 20 yr) without a diagnosis of asthma, in 12 subjects with mild asthma, and in 12 healthy controls, through immunohistochemistry and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 105 extracted citations

Similar Papers

Loading similar papers…