Evidence of adoption, monozygotic twinning, and low inbreeding rates in a large genetic pedigree of polar bears

  title={Evidence of adoption, monozygotic twinning, and low inbreeding rates in a large genetic pedigree of polar bears},
  author={Ren{\'e} M Malenfant and David W. Coltman and Evan S. Richardson and Nicholas J. Lunn and Ian Stirling and Elizabeth M. Adamowicz and Corey S. Davis},
  journal={Polar Biology},
Multigenerational pedigrees have been developed for free-ranging populations of many species, are frequently used to describe mating systems, and are used in studies of quantitative genetics. Here, we document the development of a 4449-individual pedigree for the Western Hudson Bay subpopulation of polar bears (Ursus maritimus), created from relationships inferred from field and genetic data collected over six generations of bears sampled between 1966 and 2011. Microsatellite genotypes for 22… 
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This represents one of the first direct comparisons of pedigree construction using different markers in the same set of individuals, and the SNPs described here will be a resource for continued pedigree construction, and future research in Weddell seals.
Incidence of Multiple Paternity and Inbreeding in High-Density Brown Bear Populations on the Shiretoko Peninsula, Hokkaido, Japan.
The results suggest that male-biased natal dispersal effectively limits mating between closely related individuals (aside from fathers and daughters) in brown bears, similar to a Scandinavian population.
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A 4449‐individual pedigree and an array of 5,433 single nucleotide polymorphisms (SNPs) to provide the first quantitative genetic study of polar bears and suggested that variation in body length was associated with genes in the regulatory cascade of cyclin expression, which has previously been associated with body size in mice.
Pedigree reconstruction reveals large scale movement patterns and population dynamics of wolverines (Gulo gulo) across Fennoscandia
Dispersal is a biological imperative for many species, facilitating gene flow and influencing population dynamics. Modern landscapes are increasingly fragmented, leaving species that rely on
Assessing polar bear (Ursus maritimus) population structure in the Hudson Bay region using SNPs
Using SNPs to detect fine‐scale population structure in polar bears from the Hudson Bay region and compared the results to the current designations demonstrating the value of using SNPs for fine-scale population delineation in polar Bears.
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At the spatial scale of a species' range, variation due to phylogeography and anthropogenically influenced diversity will overwhelm accuracy issues between studies and reveal broad spatial patterns, which may help managers identify populations in need of genetic management.
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The results support a growing body of evidence that suggests that male-biased size dimorphism and polygynous mating systems need not be associated with high variance in male mating and/or reproductive success.
Quantitative analysis of connectivity in populations of a semi-aquatic mammal using kinship categories and network assortativity.
K kinship networks were built and a method based on the assortativity coefficient, which measures the proportion between observed and expected kinship relationships across a barrier, enabled us to infer that the most important barrier in the area was the watershed divide between the rivers, followed by a dam on one of the rivers.
Who are you? A framework to identify and report genetic sample mix‐ups
An easy‐to‐follow sample verification framework that can utilise existing metadata, including species, population structure, sex and pedigree information, is presented and helped to confirm 488 individuals, correct another 20 bird‐genotype links, and detect hundreds of incorrect sample IDs.
The mystery of monozygotic twinning II: What can monozygotic twinning tell us about Amyoplasia from a review of the various mechanisms and types of monozygotic twinning?
  • J. Hall
  • Medicine
    American journal of medical genetics. Part A
  • 2021
Amyoplasia, a specific nongenetic form of arthrogryposis, appears to occur in spontaneous MZ twinning and may be related to twin–twin transfusion.


The mating system of polar bears: a genetic approach
The mating system of polar bears in the Barents Sea appears to be promiscuous, usually with a single successful father siring full siblings within a year, but with consecutive litters of a mother being fathe...
COLONY: a program for parentage and sibship inference from multilocus genotype data
Pedigrees, depicting genealogical relationships between individuals, are important in several research areas. Molecular markers allow inference of pedigrees in wild species where relationship
Wild pedigrees: the way forward
  • J. Pemberton
  • Biology
    Proceedings of the Royal Society B: Biological Sciences
  • 2008
In outbred diploid populations, the pedigree approach is superior to analyses based on marker-based pairwise estimators of coancestry, and even where only imprecise pedigrees are available it is possible to estimate the consequences of imprecision for the questions of interest.
Genetic linkage map of a wild genome: genomic structure, recombination and sexual dimorphism in bighorn sheep
A first-generation bighorn sheep linkage map is developed that will facilitate future studies of the genetic architecture of trait variation in this species and suggests that domestication may have played a role in altering patterns of heterochiasmy.
Estimation of pairwise relatedness with molecular markers.
Two examples are given in which the new estimators are applied to natural populations, one that reveals isolation-by-distance in an annual plant and the other that suggests a genetic basis for a coat color polymorphism in bears.
FRANz: reconstruction of wild multi-generation pedigrees
A software package for pedigree reconstruction in natural populations using co-dominant genomic markers such as microsatellites and single nucleotide polymorphisms (SNPs) and the parentage inference is robust even in the presence of genotyping errors.
Genetic Analysis of Twinning in Antarctic Fur Seals (Arctocephalus gazella)
The results provide novel insights into the reproductive ecology of fur seals and also support an earlier study showing that molecular genetic analysis can provide an effective means of validating field observations of pinniped twins.
Sex‐biased natal dispersal and inbreeding avoidance in American black bears as revealed by spatial genetic analyses
Evidence supports the hypothesis that inbreeding avoidance is achieved by means of male‐biased dispersal but also indicates that competition (for mates or resources) modifies dispersal patterns.
Single nucleotide polymorphism-based dispersal estimates using noninvasive sampling
The results illustrate the potential of using a combination of noninvasively collected samples at high resolution and specialized SNPs for pedigree-based dispersal models and are in agreement with the previously identified pattern of male-biased dispersal.
A genome scan for quantitative trait loci in a wild population of red deer (Cervus elaphus).
An attempt to map quantitative trait loci for birth weight in an unmanipulated, wild population of red deer (Cervus elaphus) is described, the first time that a QTL for any trait has been mapped in a wild mammal population.