Evidence of a Genetic Contribution to Functional Bowel Disorder

  title={Evidence of a Genetic Contribution to Functional Bowel Disorder},
  author={Allen Morris-Yates and Nicholas J Talley and Philip M. Boyce and Sanjay Nandurkar and Gavin Andrews},
  journal={American Journal of Gastroenterology},
Objective:Anecdotally, functional bowel disorders (FBD) such as the irritable bowel syndrome appears to cluster in some families, but no studies have investigated the heritability of FBD. We aimed to investigate the influence of heritable factors in FBD.Methods:Same sex twin pairs enrolled in the Australian Twin Registry completed a structured interview that included questions related to symptoms consistent with FBD: abdominal pain, diarrhea, constipation, excessive gas or bloating, and nausea… CONTINUE READING


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