Evidence indicating that pig renal phosphate-activated glutaminase has a functionally predominant external localization in the inner mitochondrial membrane.

@article{Kvamme1991EvidenceIT,
  title={Evidence indicating that pig renal phosphate-activated glutaminase has a functionally predominant external localization in the inner mitochondrial membrane.},
  author={Elling Kvamme and Ingeborg Aa. Torgner and Bj\org Roberg},
  journal={The Journal of biological chemistry},
  year={1991},
  volume={266 20},
  pages={13185-92}
}
Phosphate-activated glutaminase in intact pig renal mitochondria was inhibited 50-70% by the sulfhydryl reagents mersalyl and N-ethylmaleimide (0.3-1.0 mM), when assayed at pH 7.4 in the presence of no or low phosphate (10 mM) and glutamine (2 mM). However, sulfhydryl reagents added to intact mitochondria did not inhibit the SH-enzyme beta-hydroxybutyrate dehydrogenase (a marker of the inner face of the inner mitochondrial membrane), but did so upon addition to sonicated mitochondria. This… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

Glutamate transport and renal function.

The American journal of physiology • 1999
View 3 Excerpts
Highly Influenced

Glutamate transport and renal function.

American journal of physiology. Renal physiology • 1999
View 3 Excerpts
Highly Influenced

Glutamate Release

Neurochemical Research • 2015
View 1 Excerpt

Glutamine homeostasis and mitochondrial dynamics.

The international journal of biochemistry & cell biology • 2009
View 3 Excerpts

Similar Papers

Loading similar papers…