Evidence in favour of ancient octaploidy in the vertebrate genome.

@article{Gibson2000EvidenceIF,
  title={Evidence in favour of ancient octaploidy in the vertebrate genome.},
  author={Toby J. Gibson and J{\"u}rg Spring},
  journal={Biochemical Society transactions},
  year={2000},
  volume={28 2},
  pages={259-64}
}
Vertebrate genomes are larger than invertebrates and show evidence of extensive gene duplication, including many collinear chromosomal segments. On the basis of this intra-genomic synteny, it has been proposed that two rounds of whole genome duplication (octaploidy) occurred early in the vertebrate lineage. Recently, this early vertebrate octaploidy has been challenged on the basis of gene trees. We report new linkage groups encompassing the matrilin (MATN), syndecan (SDC), Eyes Absent (EYA… CONTINUE READING

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