Evidence in favor of the mechanical (intrauterine torsion) theory over the endocrinopathy (cryptorchidism) theory in the pathogenesis of testicular agenesis.

@article{Huff1991EvidenceIF,
  title={Evidence in favor of the mechanical (intrauterine torsion) theory over the endocrinopathy (cryptorchidism) theory in the pathogenesis of testicular agenesis.},
  author={Dale S. Huff and Huiyun Wu and Howard McC Snyder and Faruk Hadziselimovic and Bruce Blythe and John W. Duckett},
  journal={The Journal of urology},
  year={1991},
  volume={146 2 ( Pt 2)},
  pages={630-1}
}
There are 2 competing theories regarding the pathogenesis of testicular agenesis--the endocrinopathy/cryptorchidism and the mechanical/intrauterine torsion theories. We compare the number of Leydig cells, total number of germ cells and the transformation of adult dark spermatogonia into primary spermatocytes in semithin sections of testicular biopsies from 59 contralateral descended testes of patients with testicular agenesis with those in the contralateral descended testes from 250 patients… CONTINUE READING

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