Evidence in bronchoalveolar lavage for third type immune reactions in hypersensitivity pneumonitis.

Abstract

... u. ... .... _n of lung parenchyma by CD8+ cells ~hl!eOI~cut immunohistological observations f!CU:ii~'J""' CD8+ infiltrate in the group of continued to ~ regularly exposed, and of CD4+ cells after 6 months in the lungs of were not. indicate that alveolitis in RP patients is a and its intensity might be modulated by to relevant antigens, amount of antigen of sensitization, thus explaining the BAL lymphocytosis observed in patients exposed to the specific antigens compared are noL Increased cells with supprcssor/cyin the lung of these patients is related to a local immunological response . These mechanisms may be relevant in the pathogenesis of HP.

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Cite this paper

@article{Pesci1990EvidenceIB, title={Evidence in bronchoalveolar lavage for third type immune reactions in hypersensitivity pneumonitis.}, author={Alberto Pesci and Giuseppina Bertorelli and Pierpaolo Dall'aglio and Gabriella Neri and Dario Olivieri}, journal={The European respiratory journal}, year={1990}, volume={3 3}, pages={359-61} }