Evidence for vascular macrophage migration inhibitory factor in destabilization of human atherosclerotic plaques.

Abstract

OBJECTIVE Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine and has been shown to play a role in pathogenesis of atherosclerosis. The aim of this study is to investigate the potential role of MIF in the destabilization of atherosclerotic plaques by stimulation of vascular MMP-1 expression. METHODS MIF and matrix metalloproteinase… (More)

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@article{Kong2005EvidenceFV, title={Evidence for vascular macrophage migration inhibitory factor in destabilization of human atherosclerotic plaques.}, author={Yao-zhong Kong and Xiao-ru Huang and Xiaosen Ouyang and Jei-Ju Tan and Guenter Fingerle-Rowson and Michael Bacher and Wei Mu and Larry A Scher and Lin Leng and Richard J. Bucala and Hui Lan}, journal={Cardiovascular research}, year={2005}, volume={65 1}, pages={272-82} }