Evidence for triiodothyronine receptors in human endometrium and myometrium.

  title={Evidence for triiodothyronine receptors in human endometrium and myometrium.},
  author={James l. Kirkland and Venkat Ramaiah Mukku and Mattie N Hardy and Robert Young},
  journal={American journal of obstetrics and gynecology},
  volume={146 4},
Thyroid gland dysfunction in humans may cause various female reproductive tract disorders. Thyroid hormone action is thought to be mediated by high-affinity low-capacity receptor proteins located in the nucleus. The studies detailed in this report were undertaken to determine if uterine nuclei contain specific high-affinity receptors for thyroid hormone. Nuclei from human endometrium and myometrium were prepared by homogenization and centrifugation following routine surgical procedures. With… CONTINUE READING


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