Evidence for the use of probiotics and prebiotics in inflammatory bowel disease: a review of clinical trials.

@article{Hedin2007EvidenceFT,
  title={Evidence for the use of probiotics and prebiotics in inflammatory bowel disease: a review of clinical trials.},
  author={Charlotte R H Hedin and Kevin M. Whelan and James Oliver Lindsay},
  journal={The Proceedings of the Nutrition Society},
  year={2007},
  volume={66 3},
  pages={307-15}
}
Human subjects and their enteric microbiota have evolved together to reach a state of mutual tolerance. Mounting evidence from both animal models and human studies suggests that inflammatory bowel disease (IBD) represents a malfunction of this relationship. The enteric microecology therefore represents an attractive therapeutic target with few side effects. Probiotics and prebiotics have been investigated in clinical trials as treatments for IBD, with conflicting results. The evidence for the… CONTINUE READING

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