Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population.

@article{Tsurumaru2006EvidenceFT,
  title={Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population.},
  author={Masako Tsurumaru and Eiji Kawasaki and Hiroaki Ida and Kiyoshi Migita and Akie Moriuchi and Keiko Fukushima and Tetsuya Fukushima and Norio Abiru and Hironori Yamasaki and Shinsuke Noso and Hiroshi Ikegami and Takuya Awata and Hitoshi Sasaki and Katsumi Eguchi},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 8},
  pages={3138-43}
}
CONTEXT Recently, an association of a single nucleotide polymorphism, 163A>G encoding M55V, in the gene SUMO4, which has been shown to be a negative feedback regulator for nuclear factor kappaB, has been reported in type 1 diabetes. OBJECTIVE To establish whether SUMO4 locus contributes to the genetic susceptibility to other autoimmune disorders, a case-control analysis was carried out using genomic DNA from type 1 diabetes, autoimmune thyroid disease (AITD), rheumatoid arthritis (RA), and… CONTINUE READING
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