Evidence for the role of phosphatidylcholine-specific phospholipase in experimental subarachnoid hemorrhage in rats

@article{Li2015EvidenceFT,
  title={Evidence for the role of phosphatidylcholine-specific phospholipase in experimental subarachnoid hemorrhage in rats},
  author={Bo Li and Haiying Li and Zhong Wang and Yibing Wang and Gang Chen},
  journal={Experimental Neurology},
  year={2015},
  volume={272},
  pages={145-151}
}
  • Bo Li, Haiying Li, +2 authors Gang Chen
  • Published in Experimental Neurology 2015
  • Medicine
  • Neuron apoptosis and inflammatory responses contribute to subarachnoid hemorrhage (SAH)-induced early brain injury (EBI), which is the main aspect that affects patients' outcome. Previous research has demonstrated that phosphatidylcholine-specific phospholipase C (PC-PLC) plays critical roles in cell apoptosis and various inflammatory responses, and that tricyclodecan-9-yl-xanthogenate (D609), a well known PC-PLC inhibitor, is a powerful agent to protect brain from cerebral ischemic injury and… CONTINUE READING

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