Evidence for the participation of mast cells in the innate resistance of mice to Schistosoma mansoni: effects on in vivo treatment with the ionophore 48-80.

Abstract

1. Evidence is presented for the participation of mast cells in the resistance of mice to infection by Schistosoma mansoni. 2. Intravenous injection of 1 micrograms/g body weight of the ionophore 48-80, a potent mast cell degranulator, significantly reduced (42-62%) the histamine content of the ear tissue of normal mice and either increased or decreased… (More)

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