Evidence for the involvement of sperm angiotensin converting enzyme in fertilization.

@article{Foresta1991EvidenceFT,
  title={Evidence for the involvement of sperm angiotensin converting enzyme in fertilization.},
  author={C. Foresta and Roberto Mioni and Marco Rossato and Alessandro Varotto and Mg Zorzi},
  journal={International journal of andrology},
  year={1991},
  volume={14 5},
  pages={
          333-9
        }
}
Recently it has been observed that ejaculated human sperm possess high angiotensin converting enzyme (ACE) activity and that this enzyme is released during the process of capacitation. This observation raises the possibility that ACE may be involved in the fertilization process. To verify this hypothesis, we tested the effects of a potent ACE inhibitor, Captopril, on acrosome reaction induced by capacitating medium (3.5% HSA-added BWW) and on ability of human capacitated spermatozoa to… CONTINUE READING

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