Evidence for the involvement of heme oxygenase-1 in the antidepressant-like effect of zinc.

@article{Manosso2017EvidenceFT,
  title={Evidence for the involvement of heme oxygenase-1 in the antidepressant-like effect of zinc.},
  author={Luana Meller Manosso and Morgana Moretti and Julia Macedo Rosa and Mauricio P Cunha and Ana L{\'u}cia S Rodrigues},
  journal={Pharmacological reports : PR},
  year={2017},
  volume={69 3},
  pages={497-503}
}
BACKGROUND Considering that heme oxygenase-1 (HO-1) and the brain-derived neurotrophic factor (BDNF)-mediated pathway are involved in the pathophysiology of depression and that zinc has been shown to exert beneficial effects in the management of depression, this study investigated the influence of these targets on the antidepressant-like effect of zinc… CONTINUE READING