Evidence for the involvement of endogenous ATP and P2X receptors in TMJ pain.

@article{Oliveira2005EvidenceFT,
  title={Evidence for the involvement of endogenous ATP and P2X receptors in TMJ pain.},
  author={Maria Cl{\'a}udia Gonçalves Oliveira and Carlos Am{\'i}lcar Parada and Maria Cec{\'i}lia Ferraz de Arruda Veiga and Luciane Lacerda Franco Rocha Rodrigues and S. P. Barros and Cl{\'a}udia Herrera Tambeli},
  journal={European journal of pain},
  year={2005},
  volume={9 1},
  pages={87-93}
}
Evidence is accumulating which supports a role for ATP in the initiation of pain by acting on P2X receptors expressed on nociceptive afferent nerve terminals. To investigate whether these receptors play a role in temporomandibular (TMJ) pain, we studied the presence of functional P2X receptors in rat TMJ by examining the nociceptive behavioral response to the application of the selective P2X receptor agonist alpha,beta-methylene ATP (alpha,beta-meATP) into the TMJ region of rat. The involvement… CONTINUE READING