Evidence for the existence of mammalian acetoacetate decarboxylase: with special reference to human blood serum.

@article{Stekelenburg1972EvidenceFT,
  title={Evidence for the existence of mammalian acetoacetate decarboxylase: with special reference to human blood serum.},
  author={G. V. van Stekelenburg and G. Koorevaar},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1972},
  volume={39 1},
  pages={
          191-9
        }
}
In this article evidence is presented for the existence of mammalian acetoacetate decarboxylase (acetoacetate carboxy-lyase: E.G. 4.1.1.4). From experiments with human blood serum the presence of a non-ultrafiltrable activator, accelerating the decomposition of acetoacetate into acetone and carbon dioxide, is established. Kinetic studies about this activator are performed by means of repeated gas Chromatographie determination of acetone in the head space vapour. From the experiments with… Expand
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