Evidence for the evolution of a single component phenol/cresol hydroxylase from a multicomponent toluene monooxygenase

Abstract

We have previously reported on the organization of a unique toluene-3-monooxygenase pathway for the degradation of alkyl-substituted petroleum hydrocarbons including characteristics of the second step in the pathway transforming phenols to catechols. In the present work we have focused on the regulation and unusual genetic organization of this metabolic… (More)
DOI: 10.1038/sj.jim.2900453

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