Evidence for the detection of the infectious pancreatic necrosis virus polyprotein and the 17-kDa polypeptide in infected cells and of the NS protease in purified virus.

@article{Magyar1994EvidenceFT,
  title={Evidence for the detection of the infectious pancreatic necrosis virus polyprotein and the 17-kDa polypeptide in infected cells and of the NS protease in purified virus.},
  author={George Magyar and Peter Dobos},
  journal={Virology},
  year={1994},
  volume={204 2},
  pages={580-9}
}
The larger genome segment A of infectious pancreatic necrosis virus (IPNV) contains two open reading frames (ORFs): (i) the large ORF encodes a 106-kDa polyprotein (PP) (NH2-pVP2-NS-VP3-COOH) which is cotranslationally cleaved by the NS protease to generate the major capsid polypeptides VP2 and VP3; (ii) the second small ORF, which overlaps the 5' end of the PP ORF but in a different reading frame, encodes a 17-kDa arginine-rich polypeptide. Hitherto, neither the PP nor the 17-kDa polypeptide… CONTINUE READING

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